BUTYL BROMIDE

BUTYL BROMIDE - Names and Identifiers

Name	1-Bromobutane
Synonyms	1-Brombutan Bromobutane bromo butane BUTYL BROMIDE 1-BROMOBUTANE 1-bromo-butan N-Bromobutane 1-Bromobutane 1-butylbromide Butane, bromo- N-BUTYL BROMIDE Butane,1-bromo- n-Butyl bromide (4-bromobutoxy)benzene 1-BroMobutane, Reagent
CAS	109-65-9
EINECS	203-691-9
InChI	InChI=1/C10H13BrO/c11-8-4-5-9-12-10-6-2-1-3-7-10/h1-3,6-7H,4-5,8-9H2
InChIKey	MPPPKRYCTPRNTB-UHFFFAOYSA-N

BUTYL BROMIDE - Physico-chemical Properties

Molecular Formula	C4H9Br
Molar Mass	137.02
Density	1.276g/mLat 25°C(lit.)
Melting Point	-112 °C
Boling Point	100-104°C(lit.)
Flash Point	23 °C
Water Solubility	0.608 g/L (30 ºC)
Solubility	0.6g/l
Vapor Presure	150 mm Hg ( 50 °C)
Vapor Density	4.7 (vs air)
Appearance	Liquid
Color	Clear colorless to light yellow
Odor	characteristic odor
Merck	14,1553
BRN	1098260
Storage Condition	Store below +30°C.
Stability	Stable. Flammable - note low flash point. Incompatible with strong oxidizing agents, strong bases.
Explosive Limit	2.8-6.6%, 100°F
Refractive Index	n20/D 1.439(lit.)
Physical and Chemical Properties	This product is colorless, transparent and aromatic liquid, M.P.-112 ℃, B. p.100 ~ 104 ℃,n20D 1.4390, relative density 1.276,f. P.75f (23 ℃), insoluble in water, soluble in alcohol, ether and chloroform and other organic solvents.
Use	Used as pharmaceutical, dye, pesticide intermediates

BUTYL BROMIDE - Risk and Safety

Risk Codes	R11 - Highly Flammable R36/37/38 - Irritating to eyes, respiratory system and skin. R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R10 - Flammable
Safety Description	S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S60 - This material and its container must be disposed of as hazardous waste. S37/39 - Wear suitable gloves and eye/face protection
UN IDs	UN 1126 3/PG 2
WGK Germany	2
RTECS	EJ6225000
TSCA	Yes
HS Code	29033036
Hazard Class	3
Packing Group	II
Toxicity	LD50 orally in Rabbit: 2761 mg/kg

BUTYL BROMIDE - Nature

Open Data Verified Data

colorless liquid. Relative density 1. 276~279(20 ℃), melting point -112.4 ℃. Boiling point 101.6 °c. Boiling range (95% distillation) 100~120 deg C. Refractive index 1. 4398 (20 °c). Insoluble in water, soluble in alcohol, ether. Stable nature, but easy to fire at room temperature.

Last Update：2024-01-02 23:10:35

BUTYL BROMIDE - Preparation Method

Open Data Verified Data

1. Bromination of n-butanol
2. Sulfuric acid catalytic method

Last Update：2022-01-01 10:14:45

BUTYL BROMIDE - Use

Open Data Verified Data

It is used in the synthesis of the anesthetic tetracaine hydrochloride and also in the production of dyes and fragrances.

Last Update：2022-01-01 10:14:45

BUTYL BROMIDE - Safety

Open Data Verified Data

This product is toxic and can stimulate the skin. 250kg iron drum packaging. See 2-bromopropane.

Last Update：2022-01-01 10:14:46

BUTYL BROMIDE - Reference Information

LogP	2.75
NIST chemical information	information provided by: webbook.nist.gov (external link)
EPA chemical substance information	information provided by: ofmpeb.epa.gov (external link)
Introduction	bromobutane is an important fine chemical product, mainly used in organic synthesis as an alkylating agent; it is an intermediate of the bactericide dimethiol and dimethiol; Organic phosphine compound tributylphosphine, phase transfer catalyst and surfactant tetra-n-butyl ammonium bromide. It is also used as a solvent, a rare element extractant, a raw material for the synthesis of pesticides, pharmaceuticals, dyes, spices, and a refrigerant and a solvent.
Use	1-bromobutane is an intermediate of the bactericides dimethiol and dithiol. It is used in the synthesis of the anesthetic tetracaine hydrochloride and also in the production of dyes and fragrances. used as a rare element extractant, hydrocarbon agent and organic synthesis raw materials, can also be used as raw materials for medicine, dyes and spices used as a rare element extractant, hydrocarbon agent and organic synthesis raw materials, it can also be used as the raw material of medicine, dye and perfume. It is used as the intermediate of medicine, dye and pesticide for the synthesis of anesthetic tetracaine hydrochloride, and also for the production of dye and perfume.
production method	derived from the interaction of n-butanol with bromine in the presence of red phosphorus; or from n-butanol in the presence of sulfuric acid and hydrobromic acid reaction. The mixture was mixed with n-butanol and hydrobromic acid, and sulfuric acid was added dropwise. The reaction was heated under reflux for 1.5h. The crude bromobutane was distilled, washed with water to pH 6-7, and dehydrated with anhydrous calcium chloride. The preparation method is to stir n-butanol, sodium bromide, water and sulfuric acid evenly, heat reflux for 3H, distill crude bromobutane, wash with water, and treat with cold concentrated sulfuric acid, distillation was performed to obtain the finished product. Reaction equation: CH3CH2CH2CH2OH NaBr H2SO4 → CH3CH2CH2CH2Br Na2SO4
category	flammable liquid
toxicity grade	poisoning
Acute toxicity	intraperitoneal-rat LD50: 4450 mg/kg; Intraperitoneal-mouse LD50: 1424 mg/kg
explosive hazard characteristics	explosive when mixed with air
flammability hazard characteristics	in case of fire, high temperature, oxidant flammable; hyperthermic decomposition of toxic bromide gas
storage and transportation characteristics	The warehouse is ventilated and dried at low temperature; It is stored separately from the oxidant
extinguishing agent	dry powder, dry sand, carbon dioxide, foam, 1211 extinguishing agent
spontaneous combustion temperature	509 ° F.
toxic substance data	information provided by: pubchem.ncbi.nlm.nih.gov (external link)